HORDB

General Information

ID: hor003989
Uniprot ID: NA
Protein name: locustapyrokinin
Gene name: NA
Organism: Locusta migratoria
Family: Pyrokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: EDSGDGWPQQPFVPRL
Length: 16
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Be important for biological activity on the Leucophaea hindgut
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003989_AF2.pdb

hor003989_ESM.pdb

Physical Information

Mass:	209570	Formula:	C82H118N22O26
Absent amino acids:	ACHIKMNTY	Common amino acids:	P
pI:	3.88	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	4
Hydrophobicity:	-115.63	Boman Index:	-3750
Half-Life:	1 hour	Half-Life Yeast:	30 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	42.5
Instability Index:	9663.75	Extinction Coefficient cystines:	5500
Absorbance 280nm:	366.67

Literature

PubMed ID: 2026322
Title: Isolation, Primary Structure, and Synthesis of Locustapyrokinin: A Myotropic Peptide of Locusta Migratoria